Table 1. Body/metabolic parameters at 32 weeks of age (n = 6–12), *P < 0.05, **P < 0.01, compared with non-diabetic littermates.

	CC-ctrl	CC-T1D	HC-ctrl	HC-T1D
Body weight (g)	26.97 ± 0.37	23.79 ± 0.62**	26.84 ± 0.83	24.20 ± 0.54**
Kidney/Body (% total)	0.85 ± 0.39	0.80 ± 0.74	0.76 ± 0.70	0.75 ± 0.53
Liver/Body (% total)	5.42 ± 0.24	5.48 ± 0.12	5.35 ± 0.19	5.88 ± 0.19
Epididymal mass (% total)	1.59 ± 0.11	1.48 ± 0.15	2.12 ± 0.20#	1.33 ± 0.13**
Retroperitoneal fat (% total)	0.54 ± 0.05	0.46 ± 0.06	0.81 ± 0.07##	0.39 ± 0.05**
Glucose (mmol/L)	14.11 ± 0.46	22.23 ± 0.97**	15.43 ± 0.51	20.28 ± 1.10**
HbA1c (%)	4.51 ± 0.06	5.85 ± 0.24**	4.36 ± 0.11	5.65 ± 0.25**
HbA1c (mmol/mol)	25.76 ± 0.82	40.44 ± 2.97 **	24.15 ± 2.00	38.21 ± 3.02 **
Serum insulin (pmol/L)	67.72 ± 1.97	8.46 ± 3.10**	21.10 ± 5.10#	4.57 ± 2.30**
Serum NEFA (mmol/L)	0.81 ± 0.06	1.06 ± 0.10	1.06 ± 0.23#	1.66 ± 0.18**
Serum triglycerides (mmol/L)	0.25 ± 5.54	0.67 ± 2.01*	0.93 ± 3.49***##	0.43 ± 0.72**
Serum Creatinine (μmol/L)	24.00 ± 0.55	28.67 ± 1.28*	28.00 ± 0.72*	28.00 ± 1.844*
Urine volume (mL/24 h)	0.50 ± 0.11	1.67 ± 0.57*	0.89 ± 0.16	1.62 ± 0.34*
24 h urinary albumin (mg/24 h)	7.71 ± 1.87	31.01 ± 7.00*	30.07 ± 3.87#	42.66 ± 7.55 *

^#P < 0.05, ^##P < 0.01. Compared with the control mice with the same treatment, results are expressed as mean ± SEM, n = 6–12.