. Author manuscript; available in PMC: 2017 Jun 1.

Published in final edited form as: Am Heart J. 2016 Mar 17;176:100–106. doi: 10.1016/j.ahj.2016.03.007

Table 2.

Age- and sex-adjusted (upper row) and additionally risk factor-adjusted (lower row) proportional hazards regression models for atrial fibrillation examining each biomarker separately.

Variable	Hazard Ratio	95% Confidence Interval		P Value
ADMA	1.15	1.02	1.29	0.02
ADMA	1.09	0.97	1.23	0.15

L-arginine	1.10	0.97	1.24	0.12
L-arginine	1.10	0.97	1.24	0.13

SDMA	1.02	0.90	1.15	0.76
SDMA	1.00	0.89	1.13	0.95

L-arginine/ADMA ratio	0.97	0.85	1.11	0.71
L-arginine/ADMA ratio	1.01	0.88	1.16	0.85

Hazard ratios are provided per one standard deviation increase in log_e-biomarker concentration. Models are adjusted for age, sex, height, weight, systolic blood pressure, diastolic blood pressure, current smoking, diabetes, hypertension treatment, myocardial infarction, and heart failure.

ADMA denotes asymmetric dimethylarginine; SDMA, symmetric dimethylarginine.