Table 2.
Two-way ANOVA tables assessing effects of genotype and lipopolysaccharide stimulation on β2-integrin subunit gene expression in Cln3−/− and wild type mixed bone marrow cultured cells.
| Subunit, gene | F-ratio | df | P value |
|---|---|---|---|
| CD11c, itgax | |||
| 24 hours | |||
| genotype | 0.005 | 1,6 | 0.945 |
| stimulation | 39.395 | 1,6 | 0.001 |
| genotype x stimulation | 2.012 | 1,6 | 0.206 |
| 48 hours | |||
| genotype | 0.478 | 1,6 | 0.515 |
| stimulation | 196.333 | 1,6 | <.0001 |
| genotype x stimulation | 2.251 | 1,6 | 0.184 |
| CD11b, itgam | |||
| 24 hours | |||
| genotype | 2201.588 | 1,6 | <.0001 |
| stimulation | 253.009 | 1,6 | <.0001 |
| genotype x stimulation | 128.628 | 1,6 | <.0001 |
| 48 hours | |||
| genotype | 628.928 | 1,6 | <.0001 |
| stimulation | 284.380 | 1,6 | <.0001 |
| genotype x stimulation | 174.628 | 1,6 | <.0001 |
Significant results in bold. df = degrees of freedom. Genotype = wild type vs. Cln3−/−. F-ratio = mean square of the factor/ mean square of error. The larger the F-ratio value, the greater the likelihood that the difference between the means is due to something other than chance alone.