Fig. 5.

FSTL-1 influences immunoglobulin production in response to B. burgdorferi infection. ELISA plates coated with B. burgdorferi membrane-associated proteins were probed with individual B. burgdorferi-infected DBA/1 WT and FSTL-1 hypomorphic mouse serum and detected using class- and isotype-specific secondary antibodies at (A) 14 days post infection and (B) 42 days post infection. Data are representative of at least two individual experiments with n = 10 mice/treatment group. Each ELISA was performed ≥3 times. Mean values are depicted with standard error.