Table 3.
BALP, CTX and sclerostin concentrations in the RG, WG, and CG at baseline and post-intervention
Variables | RG (n = 50) | WG (n = 50) | CG (n = 50) |
---|---|---|---|
BALP | |||
Baseline [%]a | 41.7 ± 12.8 | 41.8 ± 7.6 | 42.2 ± 10.4 |
Post-intervention [%]a | 41.8 ± 12.0 | 42.1 ± 8.4 | 42.1 ± 10.2 |
Change [%]b | +0.1 ± 5.0 | +0.9 ± 2.6 | −0.14 ± 0.57 |
P value | 0.33 | 0.05 | 0.19 |
ANOVA | P = 0.21 | ||
Post hoc tests | P RG − CG = 0.90; P RG − WG = 0.47; P WG − CG = 0.23 | ||
CTX | |||
Baseline [pg/mL] | 303.6 ± 156.8 | 247.3 ± 106.2 | 259.1 ± 110.2 |
Post-intervention [pg/mL] | 276.4 ± 143.6 | 253.9 ± 107.5 | 256.7 ± 111.2 |
Change [pg/mL]b | −27.2 ± 33.5 | +6.6 ± 30.7 | −2.4 ± 14.6 |
P value (paired t) | <0.01 | 0.11 | 0.37 |
ANOVA | P < 0.01 | ||
Post hoc tests | P RG − CG < 0.01; P RG − WG < 0.01; P WG − CG = 0.20 | ||
SCLEROSTIN | |||
Baseline [pmol/L] | 26.8 ± 14.0 | 23.6 ± 10.0 | 24.0 ± 8.8 |
Post-intervention [pmol/L] | 29.8 ± 15.7 | 29.9 ± 10.8 | 24.2 ± 8.8 |
Change [pmol/L]b | +2.9 ± 8.6 | +6.3 ± 12.1 | −0.2 ± 8.7 |
P value | 0.08 | <0.01 | 0.49 |
ANOVA | P < 0.01 | ||
Post hoc tests | P TG − CG = 0.1; P TG − WG = 0.11; P WG − CG < 0.01 |
Abbreviations: BALP bone specific alkaline phosphatase, CTX C-terminal telopeptide of type-I collagen, RG resistance exercise group, WG walking group, CG control group
aBALP expressed as a proportion of the total value of serum ALP
bDifference between baseline and post-intervention data