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. 2016 Mar 31;20(1):49–64. doi: 10.20463/jenb.2016.03.20.1.4

Table 3. Body weight in mice with subacute EtOH-induced intoxication.

Groups Body weights (g) Weight gains Liver weight
Day - 1 Day 0 [A]* Day 14 [B]* [B-A] absolute relative
Controls
Intact 21.96±1.58 19.86±1.73 23.21±2.04 3.35±0.87 0.881±0.095 3.801±0.351
EtOH 21.99±1.47 19.83±1.50 17.98±0.82a - 1.85±0.94a 0.478±0.038a 2.661±0.207a
Silymarin 21.90±1.81 19.85±1.74 20.65±1.32ab 0.80±0.51ab 0.669±0.038ab 3.246±0.196ab
HSCF treated
500 mg/kg 21.96±1.69 19.88±1.86 20.66±1.98ab 0.79±0.51ab 0.665±0.047ab 3.243±0.364ab
250 mg/kg 22.05±1.54 20.01±1.68 20.31±1.54ab 0.30±0.38ab 0.623±0.036ab 3.076±0.218ab
125 mg/kg 21.99±1.47 20.03±1.40 19.93±1.48ac - 0.10±0.86ac 0.594±0.027ab 2.995±0.240ac

Values are expressed as Means ± SD of eight mice

*All animals were overnight fasted. Day 0 means the day of first test substance administration. Day 14 means 24 hrs after the last (14th) test substance administration

a p<0.01 as compared with intact control by LSD test. b p<0.01 and c p<0.05 as compared with EtOH control by LSD test. EtOH, Ethanol; HSCF, Hoveniae Semen Cum Fructus extracts