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. 2016 Mar 31;20(1):49–64. doi: 10.20463/jenb.2016.03.20.1.4

Table 5. Hepatic TG and TNF-α contents with hepatic CYP450 2E1 activity in subacute EtOH-treated mice.

Groups Hepatic contents Hepatic CYP450 2E1 activity
(4-nitrocatechol μM/min/mg protein)
TG (mg/g tissue) TNF-α (pg/mg protein)
Controls
Intact 18.94±3.51 27.70±15.99 1.91±0.49
EtOH 136.74±21.06a 90.46±17.04a 8.03±1.55a
Silymarin 79.93±16.24ab 52.81±13.12ab 4.40±1.49ab
HSCF treated
500 mg/kg 81.19±17.88ab 53.63±12.32ab 4.45±1.10ab
250 mg/kg 98.73±15.49ab 61.89±17.33ab 5.34±0.88ab
125 mg/kg 110.26±17.64ab 67.60±13.40ab 6.06±0.97ab

Values are expressed means ±SD of ten mice.

a p<0.01 as compared with intact control mice by LSD test. b p<0.01 as compared with EtOH control mice by LSD test. EtOH, Ethanol; HSCF, Hoveniae Semen Cum Fructus extracts; CY, Cytochrome; TG, Triglyceride;TNF, Tumor necrosis factor.