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. 2016 Jun 8;13:29. doi: 10.1186/s12989-016-0141-9

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 9 — Systemic effects of Z-MWCNT exposure. a Expression of IL-6 in the heart is elevated significantly one day after lung exposure to Z-MWCNT. b IL-6 is slightly elevated in the spleen one day after Z-MWCNT exposure. c Z-MWCNT exposure caused significantly elevated IL-6 in the liver as compared to control and U-MWCNT dosed mice at one day. The number of animals per group at day one was: Control (3), U-MWCNT (4), and Z-MWCNT (4) and at 28 days was: Control (4), U-MWCNT (5), Z-MWCNT (3) . Significance is represented as * as compared to the control and # as compared to U-MWCNT, * denotes P < 0.05, ** denotes P < 0.01, and *** denotes P < 0.001