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. 2004 Jul 13;101(29):10697–10702. doi: 10.1073/pnas.0403572101

Fig. 4.

Fig. 4.

Peripheral blood T cell HLA class I- and II-restricted responses to overlapping 13-mer NY-ESO-1 peptides. Large bars and numbers represent the protein and amino acids of NY-ESO-1. Dark bars, HLA class I responses; light bars, HLA class II responses; filled bars, previously undescribed epitopes; striped bars, class I epitopes definitely or possibly described previously; dotted bars, class II epitopes definitely or possibly described previously; numbers in bold italics, responses proven to be induced by vaccination; underlined numbers, proven preexisting responses; numbers neither in bold italic nor underlined, unable to ascertain whether preexisting or induced. Numbers to the left indicate the pt number. 7 (DTH) to responses observed in T cells derived from a DTH injection site in pt 7. All pts shown had resected melanoma and received treatment at the 100+IMX dose level, except pt 39, who received NY-ESO-1 protein without IMX. Pts 7, 9, 21, and 39 were HLA-A2-positive, and pts 13, 14, 16, and 24 were HLA-A2-negative.