Table 2.
Mean and standard deviation of general parameters measured in four experimental groups of mice to evaluate the absence of toxicity of the bifidobacterial strains administered for 10 days at dose of 5 × 108 cfu per mouse and day.
| Experimentation group | Food intakea | Drink watera | Body weigh increaseb | Ratio weight/length of colonc | |
|---|---|---|---|---|---|
| (g/mouse) | (ml/mouse) | (g) | (%) | ||
| Placebo (skim milk) | 2.22 ± 0.39 | 2.52 ± 0.48 | 0.73 ± 0.17 | 3.24 ± 0.75 | 0.024 ± 0.005 |
| Strain ΔBalat_1410 | 2.49 ± 0.23 | 2.79 ± 0.34 | 0.73 ± 0.16 | 3.20 ± 0.70 | 0.024 ± 0.009 |
| Strain Balat_1410 | 2.24 ± 0.29 | 2.68 ± 0.45 | 0.85 ± 0.25 | 3.84 ± 1.13 | 0.025 ± 0.008 |
| Strain Balat_1410S89L | 2.18 ± 0.31 | 2.84 ± 0.51 | 0.66 ± 0.18 | 2.89 ± 0.78 | 0.026 ± 0.006 |
No significant statistical differences (p > 0.05) were found among the four experimental groups after one-way ANOVA study.
a
Values obtained for the whole mice group for each day of experimental procedure.
b
body weight at day 10 subtracting the body weight measured at day 0 (27.71 ± 1.11) before the experimental procedure.
c
colon weight and length determined after 10 days of experimental procedure.