Table 1. Restriction of HIV-1 by introduced Trim5α.
Source of Trim5α | HIV-1 | G89V | CsA-treated* |
---|---|---|---|
Human | 0.77 ± 0.03 | 0.77 ± 0.05 | 0.83 ± 0.03 |
AGM (CV-1) | 0.10 ± 0.02 | 0.20 ± 0.04 | 0.28 ± 0.08 |
AGM (Vero) | 0.06 ± 0.01 | 0.08 ± 0.02 | 0.11 ± 0.01 |
Rhesus | 0.11 ± 0.03 | 0.14 ± 0.02 | 0.12 ± 0.01 |
Results shown are the mean of three experiments.
CsA, cyclosporine A. Ratio of Trim5α+ cells infected/Trim5α— cells infected