TABLE 1.
Effects of IUL TCDD Exposure on Genitourinary Responses to Adult T+E2 Exposure
| Body Weight (g) | Bladder Volume (mm3/g) | Bladder Weight (mg/g) | Ventral Prostate (mg/g) | Anterior Prostate (mg/g) | Dorsolateral Prostate (mg/g) | Seminal Vesicles (mg/g) | Penile Paraphimosis (Incidence) | |
|---|---|---|---|---|---|---|---|---|
| Corn Oil T+E2 | 28.2 ± 0.7 (12) | 25 ± 8 (9) | 4.5 ± 0.5 (12) | 0.9 ± 0.1 (12) | 1.2 ± 0.1 (12) | 2.0 ± 0.3 (12) | 4.0 ± 0.7 (12) | 45% (22) |
| TCDD T+E2 | 24.3 ± 1.0* (18) | 44 ± 7 (15) | 6.7 ± 0.7* (17) | 1.1 ± 0.2 (16) | 1.2 ± 0.2 (16) | 3.2 ± 0.4* (16) | 7.9 ± 0.8* (15) | 29% (21) |
Results are mean ± SE (or incidence), with the number of replicates shown in parentheses.
*Significantly different from control (P < .05).