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. 2016 Feb 10;151(1):88–103. doi: 10.1093/toxsci/kfw026

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Published by Oxford University Press on behalf of the Society of Toxicology 2016. This work is written by US Government employees and is in the public domain in the US.

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FIG. 4. — The biomarker accurately identifies ERα modulators in a MCF-7 compendium. Assessment of the correlation between the ERα biomarker and the 10 biosets used to create the biomarker. The ERα biomarker was compared with the biosets using the Running Fisher test (Kupershmidt et al. 2010). The significance of the correlation is indicated by the −log(P value). Biosets with positive or negative correlation to the biomarker are indicated as positive or negative numbers, respectively, and are indicated as those that activate or suppress ERα.