Figure 4. Slc25a42 deficiency causes severe abnormalities in mitochondrial ultrastructure.
Longitudinal transmission electron micrographs of zebrafish skeletal muscle at 3 dpf. (A-B) Wild-type controls show normal mitochondria (black arrows). B is an enlarged image of dashed box in A. (C-D) In contrast, skeletal muscles of zebrafish injected with e3i3-MO contain mitochondria with swollen and dark inner membranes (white arrows). D is an enlarged image of dashed box in C. Scale bars: 500 nm.