Table 1. Key model parameters, including symbol, description, and sample ranges used in the LHS sensitivity analysis.
Parameter | Description | LHS range, min/max |
---|---|---|
C | Mean number of contacts per host | 4:12 |
ρ | Degree of randomness in the host contact network | NA |
1/μ | Average duration of infection | 3:10 |
1/σ | Average duration of immunity | 10:30 |
β | Probability of transmission (to a completely susceptible host) | 0.2:0.8 |
R | Probability of recombination per allele | 0.01:0.1 |
τ | Probability of allelic mutation per allele | 0.001:0.005 |
γ | Degree of cross-immunity | 0.02:4 |
N | Number of immunodominant loci | 2:4 |
P | Host population size | 100:500 |
For the LHS analysis, we used a uniform probability distribution function for each range of parameter values. NA, not applicable; min/max, ratio of minimum to maximum values.