(A) Representative images of a toluidine blue stained section of human normal skin, HTS, and transplanted xenografts at all time points showing an increased density red purple staining of mast cells similar to human HTS compared to fewer mast cells seen in normal human skin. Scale bar = 50 μm. (B) Fold changes in mast cells, measured in five randomly selected site/field. No scratch grafts (circle), scratch before grafting (square), and scratch after grafting (triangle). To see this illustration in color, the reader is referred to the web version of this article at www.liebertpub.com/wound