TABLE 2.

Summary data on effects of overexpression of αB-crystallin on cardiac sodium current I_Na

Sodium current parametera	Control vector EGFP	αB-Crystallin
Activation	n = 12	n = 12
V½ (mV)	−34.73 ± 0.79	−34.72 ± 0.61
k	6.57 ± 0.16	6.7 ± 0.12
Steady-state inactivation	n = 10	n = 11
V½ (mV)	−86.88 ± 1.09	−88.03 ± 0.39
k	5.74 ± 0.12	5.29 ± 0.10
Recovery from inactivation	n = 15	n = 14
Af	0.120 ± 0.08	0.156 ± 0.01b
τf	9.69 ± 0.40	12.88 ± 0.45b
As	0.87 ± 0.01	0.831 ± 0.01b
τs	158.033 ± 16.76	165.454 ± 14.95

^a V½, voltage of half-maximal activation; k, slope factor of voltage dependence of (in)activation; τ, time constant for development of slow inactivation; τ_f, fast time constant of recovery from inactivation; τ_s, slow time constant of recovery from inactivation; A_f, fraction of the fast component of recovery from inactivation; A_s, fraction of the slow component of recovery from inactivation. Data were shown as means ±⎭S.E.

^b p < 0.5 versus vector EGFP (Student's t test). The experiment was repeated at least three times.