FIGURE 5.

Effect of leptin on food intake. Mice (n >6 per group) were individually housed, fasted during the light cycle, and injected with saline vehicle (Veh, open bars) or leptin (Lep, gray- and black-striped bars) before being fed a pre-weighed amount of food overnight. Food intake was measured in the morning, and the experiment was repeated for 5 days. Food intake was calculated as the weight of food provided to each mouse minus the weight of food remaining in the cage. Data are mean ± S.E. *, p < 0.05 versus vehicle in each mouse group.