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. 2016 Mar 22;291(21):11216–11229. doi: 10.1074/jbc.M115.711556

FIGURE 1.

FIGURE 1.

RA regulation of UCP1 and Lcn2 expression in adipocytes. Ucp1 gene expression by norepinephrine (NE) and all-trans-retinoic acid (RA) in differentiated brown adipocytes (A) is shown. The UCP1 protein expression by RA in differentiated brown adipocytes (B) is shown. The induction of Lcn2 protein expression and secretion by RA in differentiated brown adipocytes (C) is shown. The induction of Lcn2 protein expression by RA in differentiated inguinal (D) and epididymal adipocytes (E) is shown. Serum Lcn2 in HFD-fed mice with or without RA treatment for 24 days (F) is shown. The data are represented as mean ± S.E. **, p < 0.01 versus control.