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Bound antibody EC50 and unbound receptor IC50 values
| Cell line | Antibody | Bound antibody EC50 | Unbound MET IC50 | Unbound EGFR IC50 |
|---|---|---|---|---|
| nm | nm | nm | ||
| MKN45 | Combination | 7.3 | 5.4 | 0.17 |
| Bispecific | 21.7 | 10.3 | 0.32 | |
| H1993 | Combination | 8.7 | 6.5 | 0.12 |
| Bispecific | 25.0 | 15.2 | 0.32 | |
| A431 | Combination | 0.5 | 0.93 | 0.38 |
| Bispecific | 1.4 | 0.05 | 0.92 |
