Table 5.
Univariate comparison between high- and low-lactate clearance groups
| Parameter | High lactate clearance (n=108) | Low lactate clearance (n=41) | P |
|---|---|---|---|
| Age (years) | 3.08±1.39 | 2.62±096 | 0.06 |
| Weight (kg) | 9.72±3.12 | 9.41±2.61 | 0.57 |
| Gender (male/female) | 70/38 | 27/14 | 0.89 |
| Height (cm) | 87.53±5.35 | 88.80±5.53 | 0.20 |
| Preoperative hemoglobin (g/100 mL) | 20.24±2.03 | 19.82±1.71 | 0.09 |
| Preoperative oxygen saturation (%) | 74.82±6.62 | 76.12±7.35 | 0.32 |
| Beta blocker | 98 (90.7) | 38 (92.7) | 0.07 |
| Preoperative coiling | 17 (15.7) | 15 (36.6) | 0.007* |
| CPB time (min) | 89.01±9.033 | 93.63±8.05 | 0.09 |
| Clamp time (min) | 62.68±4.07 | 64.05±5.113 | 0.12 |
| Temperature on CPB (centigrade) | 29.91±0.22 | 29.93±0.23 | 0.87 |
| Urine output on CPB (mL) | 150.85±16.03 | 151.19±17.09 | 0.55 |
| CUF (mL) | 78.37±9.18 | 79.69±7.97 | 0.52 |
| Hematocrit on CPB (%) | 33.86±1.91 | 33.38±2.44 | 0.41 |
| Duration of inotropic support (h) | 24.19±13.28 | 30.78±18.49 | <0.001* |
| Vasoactive inotropic score | 6.247±4.18 | 12.34±5.69 | <0.001* |
| Vasopressor use (%) | 8 (7.4) | 9 (22) | 0.02* |
| Duration of mechanical ventilation (h) | 11.29±4.73 | 14.56±6.73 | <0.001* |
| Duration of ICU stay (h) | 48.85±7.26 | 66.64±25.46 | 0.004* |
| Mortality | 2 (1.9) | 9 (22) | 0.03* |
| Lactate (T0) | 1.65±0.51 | 1.59±0.4 | 0.48 |
| Initial lactate (T1) | 4.65±1.07 | 4.78±0.93 | 0.47 |
| Lactate at 6 h (T6) | 3.40±1.01 | 4.57±0.82 | 0.001* |
| Lactate at 12 h (T12) | 3.11±1.01 | 4.37±0.92 | 0.001* |
| Lactate at 18 h (T18) | 2.89±0.98 | 4.27±1.08 | 0.001* |
| Lactate at 24 h (T24) | 2.4±1.02 | 4.25±1.34 | 0.001* |
| Mean postoperative lactate | 3.29±0.87 | 4.4±0.96 | 0.001* |
*P<0.05 is significant. Values are expressed as mean±SD. P<0.05 is considered significant. CPB: Cardiopulmonary bypass, ICU: Intensive Care Unit, SD: Standard deviation, CUF: Conventional ultrafiltration