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. Author manuscript; available in PMC: 2016 Nov 9.
Published in final edited form as: Nature. 2016 May 9;534(7606):277–280. doi: 10.1038/nature17675

Figure 1. Structure of RelA bound to the ribosome.

Figure 1

a, Overall view of RelA in complex with a ribosome stalled with an uncharged tRNA in the A-site. Displayed are the 50S and 30S ribosomal subunits; E-, P- and A-site tRNAs; mRNA, and RelA coloured by domain. b, Structure of the ribosome-bound form of RelA oriented from N- to C-terminus with the domain organization below showing the boundaries of the hydrolase (HYD), synthetase (SYN), TGS, Zinc-finger (ZFD) and RNA recognition motif (RRM) domains. Unmodeled flexible elements that connect RelA domains are indicated with dashed lines.