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. Author manuscript; available in PMC: 2016 Nov 9.
Published in final edited form as: Nature. 2016 May 9;534(7606):277–280. doi: 10.1038/nature17675

Extended Data Figure 5. The conformation of uncharged A-site tRNA in the presence of RelA is distinct from aminoacylated A/T-tRNA in the presence of EF-Tu.

a, The ASLs of A-site tRNA (purple) and A/T-tRNA (grey) superpose until base-pair 27:43. At this point, the A-site tRNA is distorted so that the tRNA elbow regions are separated by a 6° rotation. b, A second 11° rotation occurs at base-pair 7:66 of the acceptor stem so that the A-site tRNA in the presence of RelA is closer to the ribosomal SRL.