Table 2.
Prevalence of PAI O-122 genes in EPEC strains isolated from children with diarrhea and healthy controls
| t-EPEC | a-EPEC | All EPEC strains | |||||
|---|---|---|---|---|---|---|---|
| Genes O-122 | Diarrhea N=19 n (%) |
Control N=25 n (%) |
Diarrhea N=109 n (%) |
Control N=226 n (%) |
Diarrhea N=128 n (%) |
Control N=251 n (%) |
Total N=379 n (%) |
| PagC | 3 (15.8) | 2 (8.0) | 23 (21.1) | 40 (17.7) | 26 (20.3) | 42 (16.7) | 68 (17.9) |
| SenA | 8 (42.1) | 5 (20.0) | 37 (33.9) | 81 (35.8) | 45 (35.2) | 86 (34.3) | 131 (34.6) |
| NleB | 9 (47.4) | 5 (20.0) | 41 (37.6) | 87 (38.5) | 50 (39.1) | 92 (36.7) | 142 (37.5) |
| NleE | 8 (42.1) | 5 (20.0) | 40 (36.7) | 90 (39.8) | 48 (37.5) | 95 (37.8) | 143 (37.7) |
| lifA/efa-1 | 8 (42.1) | 4 (16.0) | 31 (28.4) | 49 (21.7) | 39 (30.5)a | 53 (21.1) | 92 (24.3) |
| Efa-N | 6 (31.6) | 3 (12.0) | 21 (19.3) | 42 (18.6) | 27 (21.1) | 45 (17.9) | 72 (19.0) |
| Efa-M | 6 (31.6) | 4 (16.0) | 27 (24.8) | 45 (19.9) | 33 (25.8) | 49 (19.5) | 82 (21.6) |
| Efa-C | 6 (31.6) | 5 (20.0) | 26 (23.9) | 42 (18.6) | 32 (25.0) | 47 (18.7) | 79 (20.8) |
| lifA/efa-1 complete b | 6 (31.6) | 3 (12.0) | 19 (17.4) | 36 (15.9) | 25 (19.5) | 39 (15.5) | 64 (16.9) |
| PAI O-122 complete c | 1 (5.3) | 0 (0.0) | 10 (9.2) | 24 (10.6) | 11 (8.6) | 24 (9.6) | 35 (9.2) |
a
, p= 0.031 (fisher exact), for the comparison between diarrhea and control strains.
b
, EPEC strains with all three regions present (efa-N, efa-M and efa-C)
c
, EPEC strains with all five genes present (pagC, senA, nleB, nleE, lifA/efa-1)
t-EPEC, typical enteropathogenic E coli; a-EPEC, atypical enteropathogenic E coli.