Table 2.
Association between genotype frequency for the IL6 174G/C gene polymorphism and tinnitus related to history of occupational noise exposure (N = 179)
| Occupational noise exposure | Genotyping | No tinnitus N (%) | With tinnitus N (%) | P value and chi-square test |
|---|---|---|---|---|
| No history | Genotypic frequency | P=0.477 | ||
| GG | 07 (8.0) | 2 (06.5) | χ2=1.48 | |
| CC | 52 (59.1) | 15 (48.4) | ||
| GC | 29 (33.0) | 14 (45.2) | ||
| Allelic frequency | P=0.475 | |||
| G | 43 (24.4) | 18 (29.0) | χ2=0.509 | |
| C | 133 (75.6) | 44 (71.0) | ||
| With history | Genotypic frequency | P=0.031 | ||
| GG | 22 (48.9) | 13 (86.7) | χ2=6.771 | |
| CC | 4 (08.9) | 00 (0.0) | ||
| GC | 19 (42.2) | 02 (13.3) | ||
| Allelic frequency | P=0.011 | |||
| G | 63 (70.0) | 28 (93.3) | χ2=6.68 | |
| C | 27 (30.0) | 02 (06.7) | ||