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Dose-dependent effect of TREM-1 antibody (4, 12 and 20 µg/ml) on the expression of MMP-1 (Panel A) and MMP-9 (Panel B) in VSMCs isolated from asymptomatic (AS) and symptomatic (S) carotid plaques and treated with TNF-α (10 ng/ml). Data are presented as mean±SD (N=3). Relative expression was normalized to GAPDH. *p<0.05, **p<0.01, ***p<0.001, ****p< 0.0001.
