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. 2016 Jun 9;11(6):e0157103. doi: 10.1371/journal.pone.0157103

Fig 4. Phylodynamic analysis of genotype A in Japan.

Fig 4

Full genomes of acute HBV genotype A samples and other Japanese HBV genotype A sequences retrieved from GenBank were used to run Skyride analysis. The Upper HPD 95% shows stable population maintaining over time while the Lower HPD 95% of effective number of viral population suggests exponential growing from early 1990 and a quick decline after 2003. However, the mean of genetic diversity (the solid black line) revealed that HBV/A population is substantially increasing from 1990 to 2003 and decreased since 2005.