Table 3. Selection sites in the S gene of acute hepatitis B viruses at 90% significance level.

Codon	Normalized dN-dS	P-value
45	25.31	0.04
184	26.60	0.04
71	-25.14	0.04
73	-44.28	0.003
82	-37.49	0.01
99	-24.18	0.05
100	-45.63	0.07
115	-26.93	0.02
117	-58.33	0.01
118	-32.20	0.2
120	-19.66	0.03
122	-56.62	0.004
125	-45.5	0.003
130	-20.37	0.07
136	-26.93	0.03
137	-21.01	0.09
144	-58.37	0.004
146	-68.66	0.002
154	-21.18	0.06
155	-80.50	0.0004
171	-23.58	0.034
190	-49.34	0.04
214	-31.29	0.02
215	-20.87	0.05

d_N: non-synonymous sites; d_S: synonymous sites