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. 2016 Jun 9;11(6):e0157081. doi: 10.1371/journal.pone.0157081

Table 6. Pregnancy outcomes for obese women in reference to weight gain.

below within above
obese GWGa * *<5kg GWG: 5-9kg GWG>9kg p-value*
n = 1297 n = 853 n = 655
PIHb
% (n) 14.3% (n = 185) 14.3% (n = 122) 15.9% (n = 104) 0.492
OR (95%CI) 0.982 (0.778–1.240) 1 1.147 (0.852–1.545)
GDMc
% (n) 21.7% (n = 331) 16.4% (n = 140) 16.3% (n = 107) <0.001
OR (95%CI) 1.703 (1.323–2.193) 1 1.030 (0.765–1.386)
SGAd
% (n) 7.4% (n = 112) 5.6% (n = 48) 5.8% (n = 38) 0.036
OR (95%CI) 1.628 (1.085–2.444) 1 1.108 (0.714–1.720)
LGAe
% (n) 14.0% (n = 213) 24.2% (n = 206) 32.8% (n = 215) <0.001
OR (95%CI) 0.595 (0.476–0.742) 1 1.470 (1.162–1.860)
Preterm birth
% (n) 13.1% (n = 199) 11.1% (n = 95) 6.7% (n = 44) <0.001
OR (95%CI) 1.459 (1.134–1.877) 1 0.591 (0.421–0.828)
Spontaneous preterm birth
% (n) 10.6% (n = 161) 8.3% (n = 71) 3.7% (n = 24) <0.001
OR (95%CI) 1.580 (1.201–2.078) 1 0.429 (0.279–0.659)
PPROMf
% (n) 3.5% (n = 54) 3.4% (n = 29) 1.7% (n = 11) 0.008
OR (95%CI) 1.280 (0.833–1.967) 1 0.486 (0.265–0.890)
Induced preterm birth
% (n) 2.5% (n = 38) 2.8% (n = 24) 3.1% (n = 20) 0.923
OR(95%CI) 1.039(0.617–1.751) 1 1.124 (0.630–2.004)
Total C/Sg
%(n) 35.6% (n = 542) 43.0% (n = 367) 45.2% (n = 296) 0.063
OR(95%CI) 0.934 (0.790–1.104) 1 1.171 (0.937–1.462)
PPHh with VDi
%(n) 18.7% (n = 285) 21.7% (n = 185) 22.7% (n = 149) 0.907
OR(95%CI) 1.038 (0.857–1.256) 1 0.994 (0.766–1.290)
PPH with C/S
%(n) 12.1% (n = 184) 11.7% (n = 100) 15.7% (n = 103) 0.031
OR(95%CI) 1.220 (0.942–1.581) 1 1.485 (1.106–1.995)
macrosomia>4000
%(n) 1.4% (n = 21) 3.3% (n = 28) 5.6% (n = 37) <0.001
OR(95%CI) 0.462 (0.260–0.818) 1 1.592 (0.906–2.799)
post-term pregnancy
%(n) 0.2% (n = 3) 1.17% (n = 10) 0.5% (n = 3) 0.035
ORj(95%CI k) 0.203 (0.056–0.736) 1 0.380(0.103–1.393)

aGWG, gestational weight gain, body mass index

bPIH, pregnancy-induced hypertension

cGDM, gestational diabetes mellitus

dSGA, small for gestational age

e LGA, large for gestational age

fPPROM, preterm prelabor rupture of membranes

gC/S,cesarian section

hPPH,postpartum hemorrhage

iVD,Vaginal delivery

jOR, odds ratio

kCI, confidence interval

* Logistic regression was used to adjust for confounding variables, including maternal age, maternal height and parity, and generalized estimating equations (GEE) for logistic regression was used to adjust for the clustering of deliveries by hospitals. The results were expressed as odds ratios (OR) and 95% confidence intervals (CI).

* * IOM Recommendation for gestational weight gain: underweight, 12.5–18 kg; normal, 11.5–16 kg; overweight, 7–11.5 kg; and obese, 5–9 kg.