Fig 1. Histology and expression of α5 integrin in synovial joints in control and α5 CKO mice.
The knee joints were harvested from control (A-C and G-I) and α5 CKO (D-F and J-L) at 4 weeks of age and subjected to histological inspection (A, D, G and J) and immunofluorescence staining of α5 integrin (B, E, H and K). A, D, G and J, the images of articular cartilage (A and D) and synovium (G and J) stained with hematoxylin-eosin. B, E, H and K, Superimposed images of α5 integrin staining (red) with DAPI nuclear staining (blue). C, F, I and L, Superimposed images of α5 integrin staining with the phase contrast images. Bar, 250 μm for A, D, G and J; 40 μm for B, C, E, F, H, I, K and L.
