Table 1. Solid sequencing data for up and down regulated genes in Ets96BRNAi versus all controls.
| Biological Process | ID | Gene Name | Ets96BRNAi | Expressed in CNS | Human homologue |
|---|---|---|---|---|---|
| log2 (fold change) | according to FlyAtlas | ||||
| Lipid/sugar homeostasis | |||||
| FBgn0029831 | CG5966 | -2,91 | Yes | PNLIP | |
| FBgn0015575 | α-Est7 | -0,99 | Yes | ||
| FBgn0032136 | Apoltp | -0,65 | Yes | ||
| FBgn0037312 | CG11999 | 3,36 | Yes | SDF2 | |
| FBgn0036549 | CG10516 | 2,05 | Yes | SPSB3 | |
| FBgn0004654 | Pgd | 2,03 | Yes | PGD | |
| FBgn0025885 | Inos | 1,29 | Yes | ISYNA1 | |
| FBgn0004045 | Yp1 | 1,10 | Yes | ||
| FBgn0001092 | Gapdh2 | 0,75 | Yes | GAPDH | |
| Translation | |||||
| FBgn0028697 | RpL15 | -0,70 | Yes | RPL15 | |
| FBgn0000556 | Ef1α48D | -0,59 | Yes | EEF1A1 | |
| FBgn0010409 | RpL18A | 1,28 | Yes | RPL18A | |
| FBgn0004404 | RpS14b | 1,13 | Yes | RPS14 | |
| FBgn0004867 | RpS2 | 0,76 | Yes | RPS2 | |
| FBgn0003279 | RpL4 | 0,66 | Yes | RPL4 | |
| FBgn0036213 | RpL10Ab | 0,64 | Yes | RPL10A | |
| FBgn0005593 | RpL7 | 0,63 | Yes | RPL7 | |
| FBgn0000100 | RpLP0 | 0,58 | Yes | RPLP0 | |
| Amino acid metabolism | |||||
| FBgn0037146 | CG7470 | -1,51 | Yes | ALDH18A1 | |
| FBgn0002565 | Lsp2 | 3,91 | Yes | ||
| FBgn0022774 | Oat | 2,26 | Yes | OAT | |
| FBgn0000150 | awd | 1,36 | Yes | NME1-NME2 | |
| FBgn0000116 | Argk | 0,76 | Yes | CKB | |
| Oxidation reduction | |||||
| FBgn0023507 | CG3835 | -1,53 | Yes | D2HGDH | |
| FBgn0030041 | CG12116 | -1,22 | Yes | ||
| FBgn0031689 | Cyp28d1 | -1,11 | Yes | ||
| FBgn0000406 | Cyt-b5-r | -1,06 | Yes | ||
| FBgn0025678 | CaBP1 | 3,24 | Yes | CABP1 | |
| FBgn0033663 | ERp60 | 2,57 | Yes | PDIA3 | |
| FBgn0013685 | mt:ND6 | 2,13 | Yes | ND6 | |
| FBgn0013684 | mt:ND5 | 1,57 | Yes | ND5 | |
| FBgn0013680 | mt:ND2 | 1,38 | Yes | ND2 | |
| FBgn0013675 | mt:CoII | 1,30 | Yes | COX2 | |
| FBgn0086254 | CG6084 | 1,29 | Yes | AKR1B15 | |
| FBgn0013678 | mt:Cyt-b | 1,26 | Yes | CYTB | |
| FBgn0016691 | Oscp | 1,16 | Yes | ATP5O | |
| FBgn0013672 | mt:ATPase6 | 1,11 | Yes | ATP6 | |
| FBgn0020236 | ATPCL | 1,00 | Yes | ACLY | |
| FBgn0010100 | Acon | 0,98 | Yes | ACO2 | |
| FBgn0013674 | mt:CoI | 0,96 | Yes | COX1 | |
| FBgn0024289 | Sodh-1 | 0,96 | Yes | SORD | |
| FBgn0000055 | Adh | 0,76 | Yes | ADH1 | |
| FBgn0013676 | mt:CoIII | 0,74 | Yes | COX3 | |
| Protein processing | |||||
| FBgn0033366 | Ance-4 | -1,31 | Yes | ||
| FBgn0005585 | Crc | 2,75 | Yes | CALR | |
| FBgn0001233 | Hsp83 | 2,19 | Yes | HSP90AB1 | |
| FBgn0036015 | CG3088 | 1,99 | Yes | ||
| FBgn0039562 | Gp93 | 1,27 | Yes | HSP90B1 | |
| FBgn0024352 | Hop | 2,06 | Yes | STIP1 | |
| FBgn0023529 | CG2918 | 1,37 | Yes | HYOU1 | |
| Immune defense | |||||
| FBgn0030262 | Vago | -1,78 | Yes | ||
| FBgn0010225 | Gel | -0,58 | Yes | ||
| FBgn0044812 | TotC | 3,71 | Yes | ||
| FBgn0012042 | AttA | 2,75 | Yes | ||
| FBgn0028396 | TotA | 1,43 | Yes | ||
| FBgn0035290 | CG1887 | 1,16 | No | ||
| FBgn0022355 | Tsf1 | 0,97 | Yes | ||
| FBgn0016687 | Nurf-38 | 0,93 | Yes | PPA2 | |
| Neuropeptide hormone signaling | |||||
| FBgn0037290 | CG1124 | 1,35 | Yes | ||
| FBgn0027586 | CG5867 | 0,96 | Yes | ||
| FBgn0042201 | Nplp3 | 0,81 | Yes |