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. 2016 Jun 9;11(6):e0157252. doi: 10.1371/journal.pone.0157252

Table 3. Associations Between Serum Potassium and Incident Diabetes, by Ethnicity (N = 5415).

Hazard ratio (95% CI)
Serum K (mmol/L) Number at risk Number of events Unadjusted incidence ratio (per 1000 pys) Model 1 Model 2
All participants 5415 1281 30.8
< 4.0 1767 208 35.0 1.23 (1.04, 1.47) 0.96 (0.75, 1.24)
4.0–4.49 804 662 29.8 0.99 (0.87, 1.12) 1.05 (0.89, 1.23)
≥ 4.5 2844 411 30.5 1.0 (Ref.) 1.0 (Ref.)
per 0.5 lower 1.11 (1.02, 1.20) 1.01 (0.91, 1.12)
p-value 0.02 0.86
White 2281 477 26.0
< 4.0 238 51 28.6 1.22 (0.89, 1.68) 0.98 (0.66, 1.45)
4.0–4.49 1117 235 25.5 1.02 (0.84, 1.23) 1.13 (0.91, 1.42)
≥ 4.5 926 191 25.9 1.0 (Ref.) 1.0 (Ref.)
per 0.5 lower 1.14 (0.99, 1.30) 1.05 (0.91, 1.22)
p-value 0.06 0.49
Chinese-American 679 175 34.0
< 4.0 160 42 34.4 0.85 (0.51, 1.40) 0.47 (0.21, 1.08)
4.0–4.49 435 107 32.2 0.75 (0.48, 1.18) 0.50 (0.26, 0.97)
≥ 4.5 84 26 43.0 1.0 (Ref.) 1.0 (Ref.)
per 0.5 lower 0.96 (0.74, 1.25) 0.85 (0.52, 1.39)
p-value 0.77 0.52
African-American 1345 290 29.2
< 4.0 270 63 31.9 1.17 (0.84, 1.63) 0.77 (0.46, 1.30)
4.0–4.49 707 148 27.9 0.96 (0.72, 1.26) 0.95 (0.64, 1.40)
≥ 4.5 368 79 29.8 1.0 (Ref.) 1.0 (Ref.)
per 0.5 lower 1.05 (0.89, 1.23) 0.88 (0.70, 1.11)
p-value 0.56 0.27
Hispanic 1110 339 41.6
< 4.0 136 52 54.0 1.51 (1.09, 2.08) 1.27 (0.81, 1.98)
4.0–4.49 585 172 39.4 1.02 (0.80, 1.29) 1.08 (0.79, 1.49)
≥ 4.5 389 115 40.9 1.0 (Ref.) 1.0 (Ref.)
per 0.5 lower 1.19 (1.00, 1.41) 1.08 (0.88, 1.33)
p-value 0.04 0.46

Model 1: adjusted for age (continuous), sex, race, and study site.

Model 2: M1 + waist circumference (continuous), BMI (continuous), smoking, family history of diabetes, education, income, alcohol use, physical activity, systolic blood pressure, antihypertensive medication use and use of other medications listed in Table 1.

Significant associations in bold. Race*serum potassium, P = 0.25