Table 4.
Comparison of clinical and mpMRI findings in men without and with pathological progression
| No Pathological Progression
 | 
Pathological Progression
 | 
||||||
|---|---|---|---|---|---|---|---|
| Median | Quartile 25 | Quartile 75 | Median | Quartile 25 | Quartile 75 | p Value | |
| Age | 62 | 54 | 68 | 65 | 58 | 68 | 0.211 | 
| PSA (ng/ml) | 4 | 1.9 | 5.6 | 7.4 | 3 | 11.2 | 0.017 | 
| Prostate vol (cm3) | 55 | 41 | 74 | 42 | 34 | 60 | 0.046 | 
| PSAD (ng/ml2) | 0.08 | 0.04 | 0.1 | 0.16 | 0.08 | 0.39 | 0.001 | 
| Change in PSAD | 0.002 | − 0.01 | 0.02 | 0.04 | 0.01 | 0.24 | 0.001 | 
| Baseline MCCL | 1.15 | 1 | 2 | 3 | 1 | 5 | 0.019 | 
| Change in index lesion vol | 0.005 | − 0.08 | 0.04 | 0.05 | − 0.01 | 0.17 | 0.061 | 
| Change in index lesion ADC | − 8 (decrease) | − 64 (no change) | 197 (increase) | − 65 (decrease) | − 134 (no change) | 37 (increase) | 0.065 | 
| Change in suspicion score (No.) | 18 (60) | 10 (33.3) | 2 (6.7) | 5 (26) | 10 (53) | 4 (21) | |