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. Author manuscript; available in PMC: 2016 Jun 9.
Published in final edited form as: J Urol. 2015 Dec 7;195(5):1421–1427. doi: 10.1016/j.juro.2015.11.055

Table 4.

Comparison of clinical and mpMRI findings in men without and with pathological progression

No Pathological Progression
Pathological Progression
Median Quartile 25 Quartile 75 Median Quartile 25 Quartile 75 p Value
Age 62 54 68 65 58 68 0.211
PSA (ng/ml) 4 1.9 5.6 7.4 3 11.2 0.017
Prostate vol (cm3) 55 41 74 42 34 60 0.046
PSAD (ng/ml2) 0.08 0.04 0.1 0.16 0.08 0.39 0.001
Change in PSAD 0.002 − 0.01 0.02 0.04 0.01 0.24 0.001
Baseline MCCL 1.15 1 2 3 1 5 0.019
Change in index lesion vol 0.005 − 0.08 0.04 0.05 − 0.01 0.17 0.061
Change in index lesion ADC − 8 (decrease) − 64 (no change) 197 (increase) − 65 (decrease) − 134 (no change) 37 (increase) 0.065
Change in suspicion score (No.) 18 (60) 10 (33.3) 2 (6.7) 5 (26) 10 (53) 4 (21)