. Author manuscript; available in PMC: 2016 Jun 9.

Published in final edited form as: J Urol. 2015 Dec 7;195(5):1421–1427. doi: 10.1016/j.juro.2015.11.055

Table 5.

Performance of mpMRI score and clinical data for prediction of pathological progression

Performance	mpMRI Progression	MCCL 3 mm or Greater (baseline)	PSAD 0.15 ng/ml²or Greater (follow up)	Any Condition Met
% Sensitivity (95% CI)	37 (16–62)	53 (29–76)	63 (38–84)	95 (74–99)
% Specificity (95% CI)	90 (74–98)	80 (61–92)	97 (83–99)	70 (51–85)
% PPV (95% CI)	69 (52–83)	63 (35–85)	92 (64–99)	67 (46–84)
% NPV (95% CI)	70 (34–93)	73 (55–87)	81 (64–92)	96 (77–99)
% Accuracy (95% CI)	69 (55–82)	69 (55–82)	84 (70–93)	80 (66–90)
OR (95% CI)	5.3 (1.2–22)	4.4 (1.3–15.4)	50 (7–448)	42 (6–364)
AUC	0.63	0.66	0.80	0.91