FIGURE 2.

Kaplan–Meier analysis of the 5-year local regional control (A), disease-free survival (B), and overall survival rate (C) for 179 patients with at least 3 minor prognostic factors and/or at least one of the major risk factors stratified by surgery, surgery plus postoperative radiotherapy (RT), or postoperative chemo-radiotherapy (CCRT). Major risk factors include positive resection margin and extracapsular extension of nodal disease. Minor risk factors include pathological T4, positive node, close margin 1 to 5 mm, tumor depth ≥1 cm, lymphatic invasion, vascular invasion, perineural invasion, and poor differentiation. CCRT = chemo-radiotherapy, RT = radiotherapy.