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. Author manuscript; available in PMC: 2016 Nov 17.
Published in final edited form as: Biochemistry. 2015 Nov 5;54(45):6756–6759. doi: 10.1021/acs.biochem.5b01042

Figure 2.

Figure 2

Representative analyses of the SERPINB12 stoichiometry of inhibition (SI) with GZMA and HPN (A) and the kass determination for GZMA (B) and HPN (C). The SI for the SERPINB12-GZMA or -HPN interaction was 2 and 1.3, respectively. The kass for the SERPINB12 inhibition of GZMA (0.9 × 104 M-1 s-1) or HPN is (1.5 × 104 M-1 s-1) were from representative experiments. The kass in the text were the means ± SD from at least three experiments.