Table 1.
Characteristics of small lymphocytic (SLL) and marginal zone lymphoma (MZL) patients enrolled on E4402
| Characteristic | All Patients (N = 131) | Randomized Patients | |
|---|---|---|---|
| RR (N = 23) | MR (N =29) | ||
| Median age | 65.5 (29.5-86.3) | 61.3 (47.3-86.3) | 65.5 (38.5-85.4) |
| Male sex (%) | 45.8 | 30.4 | 51.7 |
| White race (%) | 93 | 95.7 | 93.1 |
| PS 0 (%) | 80.2 | 87 | 93 |
| BM involvement (%) | 63.4 | 39.1 | 62.1 |
| Elevated β2M (%) | 71.7 | 60.9 | 69 |
| Elevated LDH (%) | 15.3 | 17.4 | 27.6 |
| Hgb < 12 g/dL (%) | 22 | 8.7 | 24.1 |
| Stage (%) | |||
| I-II | 1.5 | 0 | 3.4 |
| III | 27.4 | 30.3 | 20.6 |
| IV | 80.9 | 69.6 | 75.9 |
| Time from diagnosis < 1 year (%) | 93.1 | 91.3 | 89.7 |
| Histology (%) | |||
| SLL | 43.5 | 26.1 | 24.1 |
| MZL, splenic | 3.8 | 4.3 | 13.8 |
| MZL, nodal | 21.3 | 34.8 | 31 |
| MZL, extranodal | 29 | 30.4 | 27.6 |
| Unclassifiable | 2.3 | 4.3 | 3.4 |