Table 1. Patient characteristics.
Characteristics | n = 28 |
---|---|
Sex | |
Male/female | 18/10 |
Median age at transplant, yr (range) | 16.3 (1.3–21.4) |
Diagnoses, No. (%) | |
Ewing sarcoma family | 11 (39.3) |
Osteosarcoma | 6 (21.4) |
Synovial sarcoma | 3 (10.7) |
Desmoplastic small round cell tumor | 3 (10.7) |
Rhabdomyosarcoma | 2 (7.1) |
Others* | 3 (10.7) |
Treatment prior to transplant, No. (%) | |
Chemotherapy alone | 8 (28.6) |
Chemotherapy + Surgery | 10 (35.7) |
Chemotherapy + Radiotherapy | 6 (21.4) |
Chemotherapy + Surgery + Radiotherapy | 4 (14.3) |
Primary site of tumor, No. (%) | |
Soft tissue origin | 20 (71.4) |
Bone origin | 8 (28.6) |
Cause of HDCT/auto-SCT, No. (%) | |
High-risk tumor | 18 (64.3) |
Recurrent tumor | 10 (35.7) |
Tumor status prior to HDCT/auto-SCT, No. (%) | |
Complete response | 15 (53.6) |
Partial response | 5 (17.9) |
Stable disease | 2 (7.1) |
Progressive disease | 6 (21.4) |
HDCT/auto-SCT, high-dose chemotherapy and autologous stem cell transplantation.
*Others included malignant peripheral nerve sheath tumor (n = 1), epithelioid inflammatory myofibroblastic sarcoma (n = 1), and epithelioid sarcoma (n = 1).