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. 2016 May 9;31(7):1150–1159. doi: 10.3346/jkms.2016.31.7.1150

Table 4. Analysis of risk factors for clinical outcome (death) using univariate and multivariable logistic regression analyses.

Variables Univariate analysis (a) Multivariable analysis (b)
OR 95% CI P value OR 95% CI P value
Age 1.02 1.01 1.03 < 0.001 1.03 1.01 1.05 < 0.001
Sex 1.05 0.79 1.38 0.747
Anion gap 3.04 2.28 4.06 < 0.001 2.38 1.34 4.25 < 0.001
Creatinine 5.06 3.66 7.00 < 0.001 1.66 1.10 2.51 0.02
Field of use class Herbicide Reference
Insecticide 0.2 0.12 0.32 < 0.001
Surfactant 0.08 0 0.39 0.015
Fungicide 0.1 0.02 0.5 0.026
Pesticide class Bipyridylium Reference Reference
Glycine Derivative 0.04 0.02 0.08 < 0.001 0.02 0.00 0.06 < 0.001
Organophosphate 0.11 0.06 0.19 < 0.001 0.04 0.01 0.17 < 0.001
Phosphinic acid 0.04 0.02 0.09 < 0.001 0.04 0.01 0.20 < 0.001
Pyrethroid 0.06 0.03 0.14 < 0.001 0.01 0.00 0.09 < 0.001
Surfactant 0.03 0.01 0.17 0.001 0.06 0.01 0.53 0.01
Chloroacetamide 0.09 0.01 0.33 0.002 0.05 0.00 2.13 0.11
Others 0.03 0.02 0.07 < 0.001 0.02 0.00 0.13 < 0.001
Ingested volume, mL 1 1 1 0.1556
Time lag, hr* 1.03 1 1.06 0.048
APACHE II score 1.09 1.04 1.15 < 0.001
WMSCN score 1.5 1.24 1.81 < 0.001 8.87 4.37 18.03 < 0.001
ICU admission day 0.94 0.9 0.97 < 0.001 4.23 2.98 6.02 0.001
Total admission day 0.79 0.75 0.82 < 0.001 0.22 0.16 0.31 0.001

Note that age, anion gap, serum creatinine, pesticide class, Workload Management System for Critical Care Nurses (WMSCN) score, and admission day are significant risk factors for death (P < 0.001). Both the number of patients and the death rate were incomparably higher in the herbicide (bipyridylium) category than in the other pesticide categories. Therefore, the death rates in the other pesticide groups are presented in reference to the herbicide (bipyridylium) category.

APACHE II, Acute Physiology and Chronic Health Evaluation II; ICU, intensive care unit.

*time lag: arrival to the hospital after ingestion of pesticide.