Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Pharmacokinetic parameters.
| Oral | Inhaled | |
|---|---|---|
| Observed AUC(0−4h)(ng/ml × min) | 422 ± 22 | 1308 ± 119** |
| Observed Cmax(0−4h)(ng/ml) | 4.2 ± 0.3 | 8.5 ± 0.7** |
| Observed Tmax(0−4h) (min) | 240 ± 0 | 44 ± 5** |
| Urine excretion (μg) | 303 ± 43 | 378 ± 30 |
AUC, Area Under the Curve; Cmax, Maximal Serum Concentration; Tmax, Time to maximal Concentration.
Different (P ≤ 0.01) from oral.
