Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Summary of extra-colonic cancer risk for respective gene defect
| MLH1* (%) | MSH2* (%) | MSH6* (%) | PMS2 | |
|---|---|---|---|---|
| Urinary tract | 1–3 | 8–10 | 0–1 | RR renal pelvis: 50 |
| Ovary | 11 | 10 | 1 | RR 12 |
| Gastric | 8 | 2–9 | <4 | RR 0 |
| Small bowel | 5 | 3 | 0 | RR 115 |
| Prostate | – | 17 | – | RR 1.7 |
| Biliary/pancreatic | 3 | 4 | 0 | – |
| Brain | 1 | 4 | 0 | RR 2.7 |
* Life time risk by age 70
