Figure 3.

Angiotensin-converting enzyme (ACE)-2 overexpression reverses bone marrow cell infiltration. A: Reversal cohort; representative immunofluorescence images showing green fluorescent protein–positive (GFP⁺) cells (arrowheads) in GFP-chimeric, streptozotocin (STZ)–diabetic, and vehicle (Veh)–control (Con) mouse retinas. B–F: Reversal cohort; quantification of GFP⁺ cells per square millimeter in the discrete retinal layers. B: Total cells in all layers. C: Ganglion cell layer. D: Inner plexiform layer. E: Inner nuclear layer. F: Outer plexiform layer. Data are expressed as means ± SEM. ^∗P < 0.05 versus STZ-Con. Scale bar = 100 μm. GCL, ganglion cell layer; INL, inner nuclear layer; IPL, inner plexiform layer; ND, no cells detected; ONL, outer nuclear layer.