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. 2016 Jun;186(6):1568–1581. doi: 10.1016/j.ajpath.2016.02.008

Figure 4.

Figure 4

Expression of proteins related to myofiber growth in VEH- and ActRIIB-mFc–treated mice. A: Western blots reveal protein expression of growth-associated proteins in the quadriceps muscles of individual WT or Acta1 H40Y mice. B: Quantified protein expression (normalized to GAPDH expression) for each growth-associated protein shown in A. Protein extracted from the quadriceps muscle of four 16-week-old mice per treatment group were tested. ∗P < 0.05, ∗∗P < 0.01. ActRIIB, activin type IIB receptor; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; VEH, vehicle; WT, wild type.