Skip to main content
. Author manuscript; available in PMC: 2016 Jul 6.
Published in final edited form as: Am J Respir Crit Care Med. 2011 Jun 16;184(6):724–731. doi: 10.1164/rccm.201012-2033OC

Figure 3. Intermittent hypoxia induces structural aorta remodeling.

Figure 3

Vascular remodeling was assessed in mice exposed to intermittent hypoxia (IH) or air (N) for 14 days. (A) Hematoxylin-eosin stainings (10x10 magnification and digitally magnified insets). (B) Histomorphometric analysis of intima-media thickness, n=7 each. (C) Verhoeff coloration showing thicker elastic fibers in IH-mice (10x40 magnification). Elastic fiber separation (D) and smooth-muscle cell (SMC) nuclei (E) in the media (n=7 each). (F) Alcian blue coloration showing mucoid depositions between the elastic fibers in IH-mice (arrows, 10x40 magnification).