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. 2016 Jun 10;6:27430. doi: 10.1038/srep27430

Figure 6. Blockage of CD1d reduces the iROS and 8-isoprostanes level in CE challenged mice but not in LPC exposed mice.

Figure 6

(a,b) iROS levels in lung homogenate (c,d) 8-isoprostanes levels in BALF. In part a&c, vehicle control: PBS; mice sensitized and challenged with cockroach extract and pre-administered with PBS: CE-CE-PBS; with isotype: CE-CE-Isotype; or with anti-CD1d monoclonal antibody (mAb): CE-CE-mAb CD1d. In part b&d, vehicle control: PBS; mice sensitized with cockroach extract and exposed to LPC and pre-administered with PBS: CE-LPC-PBS; or with isotype: CE-LPC-Isotype; or with anti-CD1d mAb: CE-LPC-mAB CD1d. Data represent the means ± SEM of values from 4 mice. *p < 0.05 versus PBS; #p < 0.05 versus CE-CE-PBS, $p < 0.05 versus CE-LPC-PBS.