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. 2016 Jun 10;6:27660. doi: 10.1038/srep27660

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Copyright © 2016, Macmillan Publishers Limited

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Comparison of the final growth rate obtained from some variation of greediness. (a) GLU-Δtpi: results by Boltzmann equation (1) (blue ▴, top x axis) and by moment equation (2) (red ⦁, bottom x axis) at different value of β and m, respectively. (b) Results from GRAM; RMSD of the mean = 0.0616. (c,d) Results from deterministic and random (null) models; RMSD of the mean = 0.0783 and 1.94 respectively. (e,f) Results from shuffled and merged sequence of the resilencings obtained from the standard GRAM procedure; RMSD of the mean = 0.752 and 1.57, respectively). Growth rates in h⁻¹. Black horizontal lines: error bar (standard deviation). Color code for knockouts: red = ack, green = frd, violet = zwf, yellow = ppc, blue = pck, orange = tpi. Legend for carbon sources: α-ketoglutarate (AKG, Δ), glucose (GLU, ⚪), lactate (LAC, ◽), malate (MAL, ♢) and succinate (SUC, ).

Inline graphic — Comparison of the final growth rate obtained from some variation of greediness. (a) GLU-Δtpi: results by Boltzmann equation (1) (blue ▴, top x axis) and by moment equation (2) (red ⦁, bottom x axis) at different value of β and m, respectively. (b) Results from GRAM; RMSD of the mean = 0.0616. (c,d) Results from deterministic and random (null) models; RMSD of the mean = 0.0783 and 1.94 respectively. (e,f) Results from shuffled and merged sequence of the resilencings obtained from the standard GRAM procedure; RMSD of the mean = 0.752 and 1.57, respectively). Growth rates in h⁻¹. Black horizontal lines: error bar (standard deviation). Color code for knockouts: red = ack, green = frd, violet = zwf, yellow = ppc, blue = pck, orange = tpi. Legend for carbon sources: α-ketoglutarate (AKG, Δ), glucose (GLU, ⚪), lactate (LAC, ◽), malate (MAL, ♢) and succinate (SUC, ).