Figure 1. rs55705857 is associated with increased glioma risk in the Turkish population.

(a) Comparison of rs55705857 G-allele frequency (MAF) in Turkish population to other populations. Allele frequency was obtained by genotyping a total of 727 controls (316 healthy controls and 411 cancer patients). (b) 285 glioma patients of various grades and pathologies were genotyped and odds ratio (OR) of developing glioma for rs55705857-G allele carriers was determined. Error bars indicate 95% confidence interval. (c) Trio based Transmission disequilibrium test (TDT) was employed to test for association between rs55705857 genotype and glioma risk. OR: odds ratio; p-value was calculated by chi-square-test.