Figure 4. p38 MAPK knockdown rescues hippocampal LTP impairment.

(A) LTP induced by TBS in four group mice. Insert is representative waves before and after TBS application. Right graph shows the traces in a represented fEPSPs recorded in a hippocampal slice from four group mice. (B) PTP and LTP data from four group were summarized and compared together, n = 8 slices from five animals for each group, *p < 0.05, HT group vs WT group or p38^KI/+ group or p38^KI/+ &HT group. (C) I/O curves are shown (all P > 0.05).