Table 1.
Cancer type | Chemotherapy regimen | Disease state |
---|---|---|
24 h cohort | ||
Urothelial | Gemcitabine + Cisplatin | Metastatic |
Urothelial | Gemcitabine + Cisplatin | Adjuvant |
NSCLC | Gemcitabine + Cisplatin | Metastatic |
Urothelial | Gemcitabine + Cisplatin | Neoadjuvant |
Ovarian | Carboplatin + Paclitaxel | Adjuvant |
Uterine | Carboplatin + nab-Paclitaxel | Metastatic |
48 h cohort | ||
Ovarian | Carboplatin + Paclitaxel | Adjuvant |
Breast | TCH | Adjuvant |
Breast | TCH | Adjuvant |
Breast | TCH | Adjuvant |
Urothelial | Gemcitabine + Cisplatin | Neoadjuvant |
Breast | TCH | Adjuvant |
Ovarian | Carboplatin + Paclitaxel | Metastatic |
72 h cohort | ||
Ovarian | Carboplatin + Paclitaxel | Metastatic |
Urotheliala | Gemcitabine + Cisplatin | Neoadjuvant |
Uterine | Carboplatin + Paclitaxel | Adjuvant |
Breast | TCH | Neoadjuvant |
Urothelial | Gemcitabine + Cisplatin | Neoadjuvant |
Ovarian | Carboplatin + Paclitaxel | Adjuvant |
Ovarian | Carboplatin + Paclitaxel | Metastatic |
TCH Docetaxel, carboplatin, trastuzumab
aThis patient was ineligible due to BMI 20.1 (original protocol required ≥20.5 but the protocol was subsequently amended to allow patients with normal BMI ≥18.5 given a lack of weight loss observed in the first 2 cohorts) and the data were included from 2 successful fasting cycles