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. Author manuscript; available in PMC: 2016 Jun 10.
Published in final edited form as: Crit Rev Eukaryot Gene Expr. 2016;26(1):63–96. doi: 10.1615/CritRevEukaryotGeneExpr.v26.i1.70

FIG. 1.

FIG. 1

AFM images of supercoiled DNA prepared using AP mica. (A) A large-scale image with three DNA molecules in the field. (B) Zoomed image of the top-left molecule in (A). The supercoiled molecules appear as uniformly twisted filaments with a plectonemic shape [reprinted with permission from Elsevier, Copyright 2011].7